Time-Constant-Domain Spectroscopy: An Impedance-Based Method for Sensing Biological Cells in Suspension

Gas sensing using terahertz time-domain spectroscopy

A method for detection and identification of polar gases and gas mixtures based on the technique of terahertz time-domain spectroscopy is presented. This relatively new technology promises to be the first portable far-infrared spectrometer, providing a means for real-time spectroscopic measurements over a broad bandwidth up to several THz. The measured time-domain waveforms can be efficiently p...

Electrical Impedance Spectroscopy-Based Defect Sensing Technique in Estimating Cracks

A defect sensing method based on electrical impedance spectroscopy is proposed to image cracks and reinforcing bars in concrete structures. The method utilizes the frequency-dependent behavior of thin insulating cracks: low-frequency electrical currents are blocked by insulating cracks, whereas high-frequency currents can pass through thin cracks to probe the conducting bars. From various frequ...

Sensing minute changes in biological cell monolayers with THz differential time-domain spectroscopy.

We used terahertz differential time-domain spectroscopy (THz-DTDS) to measure minute changes of bovine lung microvessel endothelial cells (BLMVEC) in response to vascular endothelial growth factor (VEGF). These changes were reflected by alterations in THz wave attenuations and THz dielectric properties of the treated cells. The VEGF-induced THz attenuations of cell monolayers correlated well wi...

An Automatic Real Time Impedance Matching System for Use in an RF Electrostatics Accelerator Ion Source

Real-time monitoring primary cardiomyocyte adhesion based on electrochemical impedance spectroscopy and electrical cell-substrate impedance sensing.

The cell-substrate distance is a direct indicator of cell adhesion to extracellular matrix which is indispensable in cell culture. A real-time monitoring approach can provide a detailed profile of cell adhesion, so that enables the detecting of adhesion-related cell behavior. In this work, we report a novel real-time impedance-based method to record the adhesion profile of cardiomyocyte, overco...